ABSTRACT
Although the medical applications of He-Ne lasers remain controversial, the clinical use of these devices for a variety of analgesic and wound healing applications is steadily increasing. Research studies of the effects of He-Ne laser irradiation on biologic function are growing in number and scope. Many investigators have described successful treatment of a wide variety of painful musculoskeletal, rheumatologic, and neurologic conditions with He-Ne lasers. Since we have recently initiated studies examing the effects of He-Ne lasers on wound healing and pain relief, we investigated the effect of He-Ne laser irradiation on the healing of skin defect, abrasion, burn and on the pain relief of temporomandibular joint dysfunction in admitted patients. The total number of patients was 96. The He-Ne laser power was 1 mW, dose was 1 J/cm2 and the wavelength was 632.8 nm. Each patient underwent 2 to 8 trials of irradiation on point around the wound area and painful joint at a frequency of 2 times a week. After every 1 trial up to 8 trials, we evaluated the efficacy of He-Ne laser irradiation by checking the wound size and by questioning the patients about degree of pain. Following the estimation by patients, excellent, good, and fair were accounted as effective, and poor as noneffective. The efficacy of the laser at the end of 2 to 8 trials was noticed on 78.1%, and the degree of pain relief was 73.9%. These results suggested that the irradiation of He-Ne laser is an effective and safe treatment for wound healing and pain relief. In this overview, we are summarizing some of our results which suggest a potential usefulness of He-Ne lasers for stimulation of wound healing and pain relief. Although its clinical use can be anticipated in the future, further research is required to clarify the basic mechanisms and the preferred optical parameters, such as treatment time and intensity, for increased wound healing and pain relief.
Subject(s)
Humans , Burns , Joints , Research Personnel , Skin , Temporomandibular Joint , Wound Healing , Wounds and InjuriesABSTRACT
The ultimate goal in nerve repair is to restore sensory and motor function of the injured part. The success or failure of this goal depends upon several variables, with the mechanism of injury being one of the more crucial determining factors. At the time of nerve repair, the damaged neural tissue is resected back to what appears to be an uninjured level. However, it is often difficult to determine this level. This study was designed to compare the degree of intraneural scarring over 3-week period in experimental different injuries. In this study, nerve cut, crush, saw, and avulsion injuries were produced in male Sprague-Dawley rats. The extent of nerve damage was assessed based on histology and intraoperative observations on days 1, 8, and 21 after the post-injury. The result of this study demonstrated that the degree of injury can vary from cutting, sawing, crushing to avulsion as well as vary on period; the first 3 weeks after injury. Therefore, a dynamic pathophysiology is induced by a nerve injury. The most severe injury was caused by nerve avulsion, sawing, crushing and cutting mechanisms of injury in order. The intraoperative observation on the first day does not good predictor of the degree of injury. Especially in case of saw injury, the scope of injury was enlarged in course of time, therefore secondary repair on the nerve would be appropriate, when the progress of fibrosis was completed. The extent of injury in the avulsion group will compromise the final result if a primary neurorrhaphy is peformed. Secondary nerve grafting may be the only way to improve sensory function in these injuries. In contrast, the zone of injury in a cut nerve has a tendency to improve over the first 2 to 3 weeks. This would suggest that when an injured nerve is trimmed back to what appears to be a noninjured zone, or normal nerve, no significant additional injury is being induced.
Subject(s)
Humans , Male , Cicatrix , Fibrosis , Rats, Sprague-Dawley , Sensation , TransplantsABSTRACT
The ultimate goal in nerve repair is to restore sensory and motor function of the injured part. The success or failure of this goal depends upon several variables, with the mechanism of injury being one of the more crucial determining factors. At the time of nerve repair, the damaged neural tissue is resected back to what appears to be an uninjured level. However, it is often difficult to determine this level. This study was designed to compare the degree of intraneural scarring over 3-week period in experimental different injuries. In this study, nerve cut, crush, saw, and avulsion injuries were produced in male Sprague-Dawley rats. The extent of nerve damage was assessed based on histology and intraoperative observations on days 1, 8, and 21 after the post-injury. The result of this study demonstrated that the degree of injury can vary from cutting, sawing, crushing to avulsion as well as vary on period; the first 3 weeks after injury. Therefore, a dynamic pathophysiology is induced by a nerve injury. The most severe injury was caused by nerve avulsion, sawing, crushing and cutting mechanisms of injury in order. The intraoperative observation on the first day does not good predictor of the degree of injury. Especially in case of saw injury, the scope of injury was enlarged in course of time, therefore secondary repair on the nerve would be appropriate, when the progress of fibrosis was completed. The extent of injury in the avulsion group will compromise the final result if a primary neurorrhaphy is peformed. Secondary nerve grafting may be the only way to improve sensory function in these injuries. In contrast, the zone of injury in a cut nerve has a tendency to improve over the first 2 to 3 weeks. This would suggest that when an injured nerve is trimmed back to what appears to be a noninjured zone, or normal nerve, no significant additional injury is being induced.
Subject(s)
Humans , Male , Cicatrix , Fibrosis , Rats, Sprague-Dawley , Sensation , TransplantsABSTRACT
The Q-switched ruby laser has been used in clinics since the early 1980s. It was tried to remove tattoos at first with good effects. Thereafter, some physicians reported the usefulness of the laser in the treatment of some kinds of pigmented lesions such as nevus of Ota, freckles and lentigines. The reason why the Q-switched ruby laser has a lot of effect on tattoos and some pigmented lesions is that the laser has the function of selective photothermolysis on those cutaneous lesions. The authors have treated 185 patients with tattoos and cutaneous pigmented lesions using the Q-switched ruby laser during last 4 years ago. Patients had tattoos, nevus of Ota, freckles, lentigines, melasma, postinflammatory hyperpigmentation, and were followed up over 5 months after the end of the laser treatment. The authors analysed the results and compared them with other's results in Caucasians, and we intended to present a guide of the treatment using Q-switched ruby laser in Koreans. The results were as follows 1. Tattoos showed good results after the treatment because the most of tattoos are black or dark blue in color and cheated by amateur. We repeated the laser treatments with the interval of 2 weeks. 2. Nevus of Ota, freckles and lentigines showed good results after treatment of the Q-switched ruby laser 3. Melasma showed no improvement after the treatment. 4. The treatment of postinflammatory hyperpigmentation using the Q-switched ruby laser must be confined within a part of the lesion at the first visit of patient, because the therapeutic effects were observed in some patients only and the degree of depigmention after treatment was diverse. 5. The most common complication after Q-switched ruby laser treatment was pigmentary change, including hyperpigmentation in most of the cases and hypopigmentation in some cases. However, there was no visible scar or remarkable change of skin texture in all of the cases.
Subject(s)
Humans , Asian People , Cicatrix , Hyperpigmentation , Hypopigmentation , Lasers, Solid-State , Lentigo , Melanosis , Nevus of Ota , SkinABSTRACT
Reconstruction of the auricle is one of the most fastidious fields in plastic and reconstructive facial surgery, because the ear is made up of complex cartilage framework arid its thin skin envelope. Insertion of carved rib cartilage is the most popular method for framework fabrication. But it has some disadvantages such as donor site morbidity, lesser flexibility of rib cartilage, difficulty in carving structure and distortion of cartilage after calving. Furthermore surgeon's talent and sufficient practice are necessary for a satisfactory result. So we introduced the concept of perichondral graft to improve the framework fabrication. In 1972 Skoog and associates reported that free perichondral grafts could be used to produce new cartilage. And several other reports supported the chondrogenesis of free perichondral graft. We molded the human ear using silicone rubbed impression material. And the eat mold was wrapped up in perichodrium of rabbit ear and placed in a subcutaneous pocket in formes of graft and flap. Six and eight weeks later, rabbits were sacrified and the newly formed cartilage framework was harvested. Grossly it showed the same appearance as the human eat and elastic property of normal cartilage. In histologic examination, it showed mature structure of normal cartilage; large lacunae containing spherical chondrocytes surrounded by well defined capsule.
Subject(s)
Humans , Rabbits , Aptitude , Cartilage , Chondrocytes , Chondrogenesis , Ear , Ear Cartilage , Fungi , Plastics , Pliability , Ribs , Silicones , Skin , Tissue Donors , TransplantsABSTRACT
No abstract available.
ABSTRACT
No abstract available.